Roychowdhury, R and Das, S P and Das, S and Biswas, S and Patel, M K and Kumar, Ajay and Sarker, U and Choudhary, S P and Das, Ranjan and Yogendra, K and Gangurde, S S (2025) Advancing vegetable genetics with gene editing: a pathway to food security and nutritional resilience in climate-shifted environments. Functional & Integrative Genomics (TSI), 25. pp. 1-32. ISSN 1438-793X
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Abstract
As global populations grow and climate change increasingly disrupts agricultural systems, ensuring food security and nutritional resilience has become a critical challenge. In addition to grains and legumes, vegetables are very important for both human and animals because they contain vitamins, minerals, and fibre. Enhancing the ability of vegetables to withstand climate change threats is essential; however, traditional breeding methods face challenges due to the complexity of the genomic clonal multiplication process. In the postgenomic era, gene editing (GE) has emerged as a powerful tool for improving vegetables. GE can help to increase traits such as abiotic stress tolerance, herbicide tolerance, and disease resistance; improve agricultural productivity; and improve nutritional content and shelf-life by fine-tuning key genes. GE technologies such as Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9 (CRISPR-Cas9) have revolutionized vegetable breeding by enabling specific gene modifications in the genome. This review highlights recent advances in CRISPR-mediated editing across various vegetable species, highlighting successful modifications that increase their resilience to climatic stressors. Additionally, it explores the potential of GE to address malnutrition by increasing the nutrient content of vegetable crops, thereby contributing to public health and food system sustainability. Additionally, it addresses the implementation of GE-guided breeding strategies in agriculture, considering regulatory, ethical, and public acceptance issues. Enhancing vegetable genetics via GE may provide a reliable and nutritious food supply for an expanding global population under more unpredictable environmental circumstances.
| Item Type: | Article |
|---|---|
| Divisions: | Global Research Program - Accelerated Crop Improvement |
| CRP: | UNSPECIFIED |
| Uncontrolled Keywords: | Breeding, CRISPR-Cas9, Crop improvement, Environmental stress, Gene editing, Vegetables |
| Subjects: | Others > Crop Improvement Others > Genetic Engineering Others > Food and Nutrition Others > Food Security |
| Depositing User: | Mr Nagaraju T |
| Date Deposited: | 14 Apr 2025 09:03 |
| Last Modified: | 14 Apr 2025 09:03 |
| URI: | http://oar.icrisat.org/id/eprint/13030 |
| Official URL: | https://link.springer.com/article/10.1007/s10142-0... |
| Projects: | UNSPECIFIED |
| Funders: | UNSPECIFIED |
| Acknowledgement: | The authors are thankful to Dr. Manish K Pandey (Principal Scientist, ICRISAT) and ICRISAT (Hyderabad, India) for research infrastructure and work facility. |
| Links: |
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