Two decades of association mapping: Insights on disease resistance in major crops

    Gangurde, S S and Xavier, A and Naik, Y D and Jha, U C and Rangari, S K and Kumar, R and Reddy, M S S and Channale, S and Elango, D and Mir, R R and Zwart, R and Laxuman, C and Sudini, H K and Pandey, M K and Punnuri, S and Mendu, V and Reddy, U K and Guo, B and Gangarao, N V P R and Sharma, V K and Wang, X and Zhao, C and Thudi, M (2022) Two decades of association mapping: Insights on disease resistance in major crops. Frontiers in Plant Science (TSI), 13. 01-22. ISSN 1664-462X

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    Abstract

    Climate change across the globe has an impact on the occurrence, prevalence, and severity of plant diseases. About 30% of yield losses in major crops are due to plant diseases; emerging diseases are likely to worsen the sustainable production in the coming years. Plant diseases have led to increased hunger and mass migration of human populations in the past, thus a serious threat to global food security. Equipping the modern varieties/hybrids with enhanced genetic resistance is the most economic, sustainable and environmentally friendly solution. Plant geneticists have done tremendous work in identifying stable resistance in primary genepools and many times other than primary genepools to breed resistant varieties in different major crops. Over the last two decades, the availability of crop and pathogen genomes due to advances in next generation sequencing technologies improved our understanding of trait genetics using different approaches. Genome-wide association studies have been effectively used to identify candidate genes and map loci associated with different diseases in crop plants. In this review, we highlight successful examples for the discovery of resistance genes to many important diseases. In addition, major developments in association studies, statistical models and bioinformatic tools that improve the power, resolution and the efficiency of identifying marker-trait associations. Overall this review provides comprehensive insights into the two decades of advances in GWAS studies and discusses the challenges and opportunities this research area provides for breeding resistant varieties.

    Item Type: Article
    Divisions: Global Research Program - Accelerated Crop Improvement
    CRP: UNSPECIFIED
    Uncontrolled Keywords: plant diseases, genome wide association studies, haplotypes, pangenomes, multiparent populations, k-mers
    Subjects: Others > Climate Change
    Others > Plant Disease
    Depositing User: Mr Nagaraju T
    Date Deposited: 22 May 2023 05:44
    Last Modified: 22 May 2023 05:44
    URI: http://oar.icrisat.org/id/eprint/12096
    Official URL: https://www.frontiersin.org/articles/10.3389/fpls....
    Projects: UNSPECIFIED
    Funders: Science Engineering Research Board (SERB; Grant No: CRG/2018/003056), Department of Science and Technology, Government of India, National Natural Science Foundation of China (31861143009, 32072090) for funding his research.
    Acknowledgement: MT acknowledges financial support from Science Engineering Research Board (SERB; Grant No: CRG/2018/003056), Department of Science and Technology, Government of India and CZ is grateful to National Natural Science Foundation of China (31861143009, 32072090) for funding his research
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