Biology-driven genebank pangenetics meet AI-powered predictions to transform crop breeding

Abbai, R and Schnurbusch, T and Cooper, M and Pandey, M K (2026) Biology-driven genebank pangenetics meet AI-powered predictions to transform crop breeding. Molecular Plant, 19 (6). pp. 1140-1143. ISSN 1674-2052

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Abstract

The modern era of crop improvement is characterized by two distinct paths: (i) biology-driven molecular genetics focused on dissecting the mechanisms underlying complex traits by a reductionist approach and (ii) data-driven quantitative genetics, which prioritizes accurate prediction of final trait performance, such as yield, without necessarily clarifying the underlying biological mechanisms. These approaches, one rooted in functional discovery and the other in statistical association, have each made significant strides, yet with limited overlap. However, their conjunction represents an emerging opportunity; integrating the functional insights from pangenetics, encompassing causal variants and haplotype diversity into artificial intelligence (AI)-based predictive frameworks, can offer a more holistic perspective for customizing and testing crop genomic ideotypes for specific agroecologies, dynamic market demands, and increasing climate uncertainties.

Item Type: Article
Divisions: Center of Excellence in Genomics and Systems Biology
Global Research Program - Accelerated Crop Improvement
CRP: UNSPECIFIED
Uncontrolled Keywords: genebank, pangenetics, AI-powered predictions, crop breeding
Subjects: Others > Plant Breeding
Others > Genetics and Genomics
Others > Gene Bank
Depositing User: Mr Nagaraju T
Date Deposited: 29 Oct 2026 11:30
Last Modified: 29 Oct 2026 11:30
URI: http://oar.icrisat.org/id/eprint/13671
Official URL: https://www.cell.com/molecular-plant/abstract/S167...
Projects: UNSPECIFIED
Funders: UNSPECIFIED
Acknowledgement: UNSPECIFIED
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