Advances in “Omics” Approaches for Improving Toxic Metals/Metalloids Tolerance in Plants

Raza, A and Tabassum, J and Zahid, Z and Charagh, S and Bashir, S and Barmukh, R and Khan, R S A and Barbosa, F Jr and Zhang, C and Chen, H and Zhuang, W and Varshney, R K (2022) Advances in “Omics” Approaches for Improving Toxic Metals/Metalloids Tolerance in Plants. Frontiers in Plant Science (TSI), 12. pp. 1-28. ISSN 1664-462X

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Abstract

Food safety has emerged as a high-urgency matter for sustainable agricultural production. Toxic metal contamination of soil and water significantly affects agricultural productivity, which is further aggravated by extreme anthropogenic activities and modern agricultural practices, leaving food safety and human health at risk. In addition to reducing crop production, increased metals/metalloids toxicity also disturbs plants’ demand and supply equilibrium. Counterbalancing toxic metals/metalloids toxicity demands a better understanding of the complex mechanisms at physiological, biochemical, molecular, cellular, and plant level that may result in increased crop productivity. Consequently, plants have established different internal defense mechanisms to cope with the adverse effects of toxic metals/metalloids. Nevertheless, these internal defense mechanisms are not adequate to overwhelm the metals/metalloids toxicity. Plants produce several secondary messengers to trigger cell signaling, activating the numerous transcriptional responses correlated with plant defense. Therefore, the recent advances in omics approaches such as genomics, transcriptomics, proteomics, metabolomics, ionomics, miRNAomics, and phenomics have enabled the characterization of molecular regulators associated with toxic metal tolerance, which can be deployed for developing toxic metal tolerant plants. This review highlights various response strategies adopted by plants to tolerate toxic metals/metalloids toxicity, including physiological, biochemical, and molecular responses. A seven-(omics)-based design is summarized with scientific clues to reveal the stress-responsive genes, proteins, metabolites, miRNAs, trace elements, stress-inducible phenotypes, and metabolic pathways that could potentially help plants to cope up with metals/metalloids toxicity in the face of fluctuating environmental conditions. Finally, some bottlenecks and future directions have also been highlighted, which could enable sustainable agricultural production.

Item Type:	Article
Divisions:	Center of Excellence in Genomics and Systems Biology
CRP:	UNSPECIFIED
Uncontrolled Keywords:	abiotic stress, CRISPR/Cas system, genomics, metabolomics, proteomics, speed breeding, miRNAomics
Subjects:	Others > Abiotic Stress Others > Genetics and Genomics
Depositing User:	Mr Nagaraju T
Date Deposited:	02 May 2024 04:00
Last Modified:	02 May 2024 04:00
URI:	http://oar.icrisat.org/id/eprint/12652
Official URL:	https://www.frontiersin.org/journals/plant-science...
Projects:	UNSPECIFIED
Funders:	National Science Foundation (NSF) of China
Acknowledgement:	AR would like to thank the Fujian Agriculture and Forestry University (FAFU) and the Fujian Provincial Government for providing Post-doc Research Fellowship. We are grateful to many scientists and colleagues for scientific discussions, which enabled the development of this up-to-date comprehensive review. We apologize to colleagues whose relevant work could not be cited due to space limitations.
Links:	Google Scholar

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