Harnessing Benefits of Finger Millet in Combating Micronutrient Malnutrition through Genetics and Genomic Approaches

Puranik, S and Philliam, A G and Ojulong, H and Yadav, R (2016) Harnessing Benefits of Finger Millet in Combating Micronutrient Malnutrition through Genetics and Genomic Approaches. In: 1st International Agrobiodiversity Congress, November 06-09, 2016, New Delhi, India.

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In developing countries, 80% deaths are attributed to continuous persistence micronutrient deficiency and associated infections and chronic diseases. Traditional crops harbouring health benefitting characteristics and micronutritional richness can deliver a low cost sustainable food-based solution for nutrition and health in such countries. Finger millet, one such traditional crop grown in most marginal areas of Africa and Asia, is a rich source of health benefitting micronutrients, phytochemicals, vitamins and several essential amino acids. The objective of this work is to use advances in genetics and genomics approaches for better understanding the genetic control of these health benefitting traits and to breed them effectively into other staple crops consumed on daily basis. A set of 190 genotypes incorporating a minicore collection of finger millet together with a number of elite breeding lines has been assembled to capture and characterise entire genetic variation associated with such traits in the crop germplasm. These genotypes have been extensively characterised for diversity in micronutrients (such as iron, zinc, calcium, magnesium, sodium, and potassium), protein and anti-nutrients (phytate and oxalate). Large-scale GBS performed on this association panel has generated 156,157 SNPs which are being used in genome-wide association studies. Our work has identified a number of genomic regions in finger millet associated with both the health benefitting traits as well as with other factors that affect their bioavailability. This work will significantly contribute in developing means of assessing how such genetic variations are distributed in other staple crops.

Item Type: Conference or Workshop Item (Paper)
Divisions: Research Program : East & Southern Africa
Uncontrolled Keywords: Finger millet, Micronutrients, Health benefitting traits, Genotyping-by sequencing, Genome-wide association study
Subjects: Mandate crops > Millets > Finger Millet
Others > Genetics and Genomics
Others > Food and Nutrition
Others > Food Security
Depositing User: Mr Ramesh K
Date Deposited: 21 Nov 2017 11:08
Last Modified: 21 Nov 2017 11:08
URI: http://oar.icrisat.org/id/eprint/10301
Acknowledgement: UNSPECIFIED
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