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dc:title "HTML Summary of #11638 \n\nGenome-wide association study uncovers genomic regions associated with grain iron, zinc and protein content in pearl millet\n\n";
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bibo:abstract "Pearl millet hybrids biofortified with iron (Fe) and zinc (Zn) promise to be part of a long-term strategy\r\nto combat micronutrient malnutrition in the arid and semi-arid tropical (SAT) regions of the world.\r\nBiofortification through molecular breeding is the way forward to achieving a rapid trait-based\r\nbreeding strategy. This genome-wide association study (GWAS) was conducted to identify significant\r\nmarker-trait associations (MTAs) for Fe, Zn, and protein content (PC) for enhanced biofortification\r\nbreeding. A diverse panel of 281 advanced inbred lines was evaluated for Fe, Zn, and PC over two\r\nseasons. Phenotypic evaluation revealed high variability (Fe: 32–120 mg kg−1, Zn: 19–87 mg kg−1, PC:\r\n8–16%), heritability (hbs2 ≥ 90%) and significantly positive correlation among Fe, Zn and PC (P = 0.01),\r\nimplying concurrent improvement. Based on the Diversity Arrays Technology (DArT) seq assay, 58,719\r\nhighly informative SNPs were filtered for association mapping. Population structure analysis showed\r\nsix major genetic groups (K = 6). A total of 78 MTAs were identified, of which 18 were associated with\r\nFe, 43 with Zn, and 17 with PC. Four SNPs viz., Pgl04_64673688, Pgl05_135500493, Pgl05_144482656,\r\nand Pgl07_101483782 located on chromosomes Pgl04 (1), Pgl05 (2) and Pgl07 (1), respectively were\r\nco-segregated for Fe and Zn. Promising genes, ‘Late embryogenesis abundant protein’, ‘Myb domain’,\r\n‘pentatricopeptide repeat’, and ‘iron ion binding’ coded by 8 SNPs were identified. The SNPs/genes\r\nidentified in the present study presents prospects for genomics assisted biofortification breeding in\r\npearl millet."^^xsd:string;
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bibo:volume "10";
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dct:date "2020-11";
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dct:title "Genome-wide association study uncovers genomic regions associated with grain iron, zinc and protein content in pearl millet"^^xsd:string;
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skos:prefLabel "Pearl Millet"@en .
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skos:prefLabel "Food and Nutrition"@en .
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bibo:issn "20452322";
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