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dc:title "HTML Summary of #11617 \n\nHigh-density SNP map facilitates fine mapping of QTLs and candidate genes discovery for Aspergillus flavus resistance in peanut (Arachis hypogaea)\n\n";
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rdfs:label "High-density SNP map facilitates fine mapping of QTLs and candidate genes discovery for Aspergillus flavus resistance in peanut (Arachis hypogaea) (Other)"^^xsd:string .
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bibo:abstract "Aflatoxin contamination in peanuts caused by Aspergillus flavus is a serious food safety issue for human health\r\naround the world. Host plant resistance to fungal infection and reduction in aflatoxin are crucial for mitigating this problem.\r\nIdentification of the resistance-linked markers can be used in marker-assisted breeding for varietal development. Here we\r\nreport construction of two high-density genetic linkage maps with 1975 SNP loci and 5022 SNP loci, respectively. Two\r\nconsistent quantitative trait loci (QTL) were identified as qRAF-3-1 and qRAF-14-1, which located on chromosomes A03\r\nand B04, respectively. QTL qRAF-3-1 was mapped within 1.67 cM and had more than 19% phenotypic variance explained\r\n(PVE), while qRAF-14-1 was located within 1.34 cM with 5.15% PVE. While comparing with the reference genome, the\r\nmapped QTLs, qRAF-3-1 and qRAF-14-1, were located within a physical distance of 1.44 Megabase pair (Mbp) and 2.22\r\nMbp, harboring 67 and 137 genes, respectively. Among the identified candidate genes, six genes with the same function were\r\nfound within both QTLs regions. In addition, putative disease resistance RPP13-like protein 1 (RPP13), lipoxygenase (Lox),\r\nWRKY transcription factor (WRKY) and cytochrome P450 71B34 genes were also identified. Using microarray analysis,\r\ngenes responded to A. flavus infection included coding for RPP13, pentatricopeptide repeat-containing-like protein, and\r\nLox which may be possible candidate genes for resistance to A. flavus. The QTLs and candidate genes will further facilitate\r\nmarker development and validation of genes for deployment in the molecular breeding programs against A. flavus in peanuts."^^xsd:string;
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bibo:issue "7";
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bibo:volume "133";
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dct:date "2020-04";
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dct:title "High-density SNP map facilitates fine mapping of QTLs and candidate genes discovery for Aspergillus flavus resistance in peanut (Arachis hypogaea)"^^xsd:string;
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skos:prefLabel "Groundnut"@en .
rdf:type skos:Concept;
skos:prefLabel "Genetics and Genomics"@en .
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skos:prefLabel "Plant Disease"@en .
rdf:type skos:Concept;
skos:prefLabel "Aflatoxins"@en .
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bibo:issn "00405752";
foaf:name "Theoretical and Applied Genetics (TSI)"^^xsd:string;
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