<mods:mods version="3.3" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mods:titleInfo><mods:title>High-density SNP map facilitates fine mapping of QTLs and candidate genes discovery for Aspergillus flavus resistance in peanut (Arachis hypogaea)</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">S A</mods:namePart><mods:namePart type="family">Khan</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">H</mods:namePart><mods:namePart type="family">Chen</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Y</mods:namePart><mods:namePart type="family">Deng</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Y</mods:namePart><mods:namePart type="family">Chen</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">C</mods:namePart><mods:namePart type="family">Zhang</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">T</mods:namePart><mods:namePart type="family">Cai</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">N</mods:namePart><mods:namePart type="family">Ali</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">G</mods:namePart><mods:namePart type="family">Mamadou</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">D</mods:namePart><mods:namePart type="family">Xie</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">B</mods:namePart><mods:namePart type="family">Guo</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">R K</mods:namePart><mods:namePart type="family">Varshney</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">W</mods:namePart><mods:namePart type="family">Zhuang</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Aflatoxin contamination in peanuts caused by Aspergillus flavus is a serious food safety issue for human health&#13;
around the world. Host plant resistance to fungal infection and reduction in aflatoxin are crucial for mitigating this problem.&#13;
Identification of the resistance-linked markers can be used in marker-assisted breeding for varietal development. Here we&#13;
report construction of two high-density genetic linkage maps with 1975 SNP loci and 5022 SNP loci, respectively. Two&#13;
consistent quantitative trait loci (QTL) were identified as qRAF-3-1 and qRAF-14-1, which located on chromosomes A03&#13;
and B04, respectively. QTL qRAF-3-1 was mapped within 1.67 cM and had more than 19% phenotypic variance explained&#13;
(PVE), while qRAF-14-1 was located within 1.34 cM with 5.15% PVE. While comparing with the reference genome, the&#13;
mapped QTLs, qRAF-3-1 and qRAF-14-1, were located within a physical distance of 1.44 Megabase pair (Mbp) and 2.22&#13;
Mbp, harboring 67 and 137 genes, respectively. Among the identified candidate genes, six genes with the same function were&#13;
found within both QTLs regions. In addition, putative disease resistance RPP13-like protein 1 (RPP13), lipoxygenase (Lox),&#13;
WRKY transcription factor (WRKY) and cytochrome P450 71B34 genes were also identified. Using microarray analysis,&#13;
genes responded to A. flavus infection included coding for RPP13, pentatricopeptide repeat-containing-like protein, and&#13;
Lox which may be possible candidate genes for resistance to A. flavus. The QTLs and candidate genes will further facilitate&#13;
marker development and validation of genes for deployment in the molecular breeding programs against A. flavus in peanuts.</mods:abstract><mods:classification authority="lcc">Groundnut</mods:classification><mods:classification authority="lcc">Genetics and Genomics</mods:classification><mods:classification authority="lcc">Plant Disease</mods:classification><mods:classification authority="lcc">Aflatoxins</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8061">2020-04</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>SPRINGER</mods:publisher></mods:originInfo><mods:genre>Article</mods:genre></mods:mods>