@article{icrisat11592, month = {March}, title = {Functional Biology and Molecular Mechanisms of Host-Pathogen Interactions for Aflatoxin Contamination in Groundnut (Arachis hypogaea L.) and Maize (Zea mays L.)}, publisher = {Frontiers Media}, year = {2020}, author = {P Soni and S S Gangurde and A Ortega-Beltran and R Kumar and S Parmar and H K Sudini and Y Lei and X Ni and D Huai and J C Fountain and S Njoroge and G Mahuku and T Radhakrishnan and W Zhuang and B Guo and B Liao and P Singam and M K Pandey and R Bandyopadhyay and R K Varshney}, pages = {1--22}, volume = {11}, note = {The fellowship of PS and SP was supported by the Council of Scientific \& Industrial Research (CSIR), Government of India. RK and RV are thankful to the Science and Engineering Research Board (SERB), Department of Science and Technology (DST), Government of India for the N-Post Doctoral Fellowship and the JC Bose Fellowship, respectively, and SG acknowledges DST for the DST-INSPIRE Fellowship.}, journal = {Frontiers in Microbiology (TSI)}, keywords = {Aspergillus flavus, Aflatoxin contamination, Host-pathogen interactions, Molecular mechanisms, QTLs, Groundnut, Maize}, url = {http://oar.icrisat.org/11592/}, abstract = {Aflatoxins are secondary metabolites produced by soilborne saprophytic fungus Aspergillus flavus and closely related species that infect several agricultural commodities including groundnut and maize. The consumption of contaminated commodities adversely affects the health of humans and livestock. Aflatoxin contamination also causes significant economic and financial losses to producers. Research efforts and significant progress have been made in the past three decades to understand the genetic behavior, molecular mechanisms, as well as the detailed biology of host-pathogen interactions. A range of omics approaches have facilitated better understanding of the resistance mechanisms and identified pathways involved during host-pathogen interactions. Most of such studies were however undertaken in groundnut and maize. Current efforts are geared toward harnessing knowledge on hostpathogen interactions and crop resistant factors that control aflatoxin contamination. This study provides a summary of the recent progress made in enhancing the understanding of the functional biology and molecular mechanisms associated with host-pathogen interactions during aflatoxin contamination in groundnut and maize.} }