@prefix ep: <http://eprints.org/ontology/> .
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  @prefix bibo: <http://purl.org/ontology/bibo/> .
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  @prefix dc: <http://purl.org/dc/elements/1.1/> .
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	dc:title "HTML Summary of #11588 \n\nFine mapping and gene cloning in the post-NGS era: advances and prospects\n\n";
	foaf:primaryTopic <http://oar.icrisat.org/id/eprint/11588> .

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	bibo:abstract "Improvement in traits of agronomic importance is the top breeding priority of crop improvement programs. Majority of\r\nthese agronomic traits show complex quantitative inheritance. Identification of quantitative trait loci (QTLs) followed by\r\nfine mapping QTLs and cloning of candidate genes/QTLs is central to trait analysis. Advances in genomic technologies\r\nrevolutionized our understanding of genetics of complex traits, and genomic regions associated with traits were employed in\r\nmarker-assisted breeding or cloning of QTLs/genes. Next-generation sequencing (NGS) technologies have enabled genomewide\r\nmethodologies for the development of ultra-high-density genetic linkage maps in different crops, thus allowing placement\r\nof candidate loci within few kbs in genomes. In this review, we compare the marker systems used for fine mapping and\r\nQTL cloning in the pre- and post-NGS era. We then discuss how different NGS platforms in combination with advanced\r\nexperimental designs have improved trait analysis and fine mapping. We opine that efficient genotyping/sequencing assays\r\nmay circumvent the need for cumbersome procedures that were earlier used for fine mapping. A deeper understanding of\r\nthe trait architectures of agricultural significance will be crucial to accelerate crop improvement."^^xsd:string;
	bibo:authorList <http://oar.icrisat.org/id/eprint/11588#authors>;
	bibo:issue "5";
	bibo:status <http://purl.org/ontology/bibo/status/peerReviewed>,
		<http://purl.org/ontology/bibo/status/published>;
	bibo:volume "133";
	dc:hasVersion <http://oar.icrisat.org/id/document/54659>;
	dct:creator <http://oar.icrisat.org/id/person/ext-28db6de6deff0640c5aeb6b93e6a699f>,
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		<http://oar.icrisat.org/id/person/ext-e02d7433aa55f226fcd78620c1dcdf80>,
		<http://oar.icrisat.org/id/person/ext-e075a964a016461ebdba1b756ee56a8d>;
	dct:date "2020-02";
	dct:isPartOf <http://oar.icrisat.org/id/repository>,
		<http://oar.icrisat.org/id/publication/ext-00405752>;
	dct:publisher <http://oar.icrisat.org/id/org/ext-1c5ddec173ca8cdfba8b274309638579>;
	dct:subject <http://oar.icrisat.org/id/subject/PLB1>,
		<http://oar.icrisat.org/id/subject/s2.13>;
	dct:title "Fine mapping and gene cloning in the post-NGS era: advances and prospects"^^xsd:string;
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	rdf:type skos:Concept;
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	foaf:givenName "R K"^^xsd:string;
	foaf:name "R K Varshney"^^xsd:string;
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