<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Genomics-Integrated Breeding for Carotenoids and Folates in Staple Cereal Grains to Reduce Malnutrition"^^ . "Globally, two billion people suffer from micronutrient deficiencies. Cereal grains provide\r\nmore than 50% of the daily requirement of calories in human diets, but they often\r\nfail to provide adequate essential minerals and vitamins. Cereal crop production in\r\ndeveloping countries achieved remarkable yield gains through the efforts of the Green\r\nRevolution (117% in rice, 30% in wheat, 530% in maize, and 188% in pearl millet).\r\nHowever, modern varieties are often deficient in essential micronutrients compared\r\nto traditional varieties and land races. Breeding for nutritional quality in staple cereals\r\nis a challenging task; however, biofortification initiatives combined with genomic tools\r\nincrease the feasibility. Current biofortification breeding activities include improving rice\r\n(for zinc), wheat (for zinc), maize (for provitamin A), and pearl millet (for iron and zinc).\r\nBiofortification is a sustainable approach to enrich staple cereals with provitamin A,\r\ncarotenoids, and folates. Significant genetic variation has been found for provitamin A\r\n(96–850 mg and 12–1780 mg in 100 g in wheat and maize, respectively), carotenoids\r\n(558–6730 mg in maize), and folates in rice (11–51 mg) and wheat (32.3–89.1 mg)\r\nin 100 g. This indicates the prospects for biofortification breeding. Several QTLs\r\nassociated with carotenoids and folates have been identified in major cereals, and the\r\nmost promising of these are presented here. Breeding for essential nutrition should be\r\na core objective of next-generation crop breeding. This review synthesizes the available\r\nliterature on folates, provitamin A, and carotenoids in rice, wheat, maize, and pearl\r\nmillet, including genetic variation, trait discovery, QTL identification, gene introgressions,\r\nand the strategy of genomics-assisted biofortification for these traits. Recent evidence\r\nshows that genomics-assisted breeding for grain nutrition in rice, wheat, maize, and\r\npearl millet crops have good potential to aid in the alleviation of micronutrient malnutrition\r\nin many developing countries."^^ . "2020-05" . . . "11" . . "Frontiers Media"^^ . . . "Frontiers in Genetics (TSI)"^^ . . . "16648021" . . . . . . . . . . . . . . . . . . . "V G"^^ . "Shobhana"^^ . "V G Shobhana"^^ . . "A"^^ . "Karthikeyan"^^ . "A Karthikeyan"^^ . . "K"^^ . "Ashok kumar"^^ . "K Ashok kumar"^^ . . "T D"^^ . "Warkentin"^^ . "T D Warkentin"^^ . . "M"^^ . "Govindaraj"^^ . "M Govindaraj"^^ . . . . . . "Genomics-Integrated Breeding for Carotenoids and Folates in Staple Cereal Grains to Reduce Malnutrition (PDF)"^^ . . . . . "fgene-11-00414.pdf"^^ . . . "Genomics-Integrated Breeding for Carotenoids and Folates in Staple Cereal Grains to Reduce Malnutrition (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #11514 \n\nGenomics-Integrated Breeding for Carotenoids and Folates in Staple Cereal Grains to Reduce Malnutrition\n\n" . "text/html" . . . "Cereals"@en . . . "Biofortification"@en . . . "Food and Nutrition"@en . .