"11511","12","archive","3170",,,"disk0/00/01/15/11","2020-05-19 09:02:06","2020-05-19 09:04:14","2020-05-19 09:02:06","article",,,"show",,,,"","","","","","","","","","",,,,"Srivastava","R K","","","","","",,"Srivastava","R K","","","","",,,,,"","",,,,,"","","ICRISAT (Patancheru)","India","Genome-Wide Association Studies and Genomic Selection in Pearl Millet: Advances and Prospects","pub","DT1","CRPS3","CG1","public",,,"Pearl millet, Genetic resources, Genomic resources, Genomic selection, Genome-wide Association studies, Molecular markers",,"Funding support from the Department of Biotechnology (DBT),
Government of India, the Biotechnology and Biological Sciences
Research Council (BBSRC), United Kingdom, and the CGIAR
Research Program on Grain Legumes and Dryland Cereals
(CRP-GLDC) is gratefully acknowledged. This work has been
published as part of the CRP-GLDC.","Pearl millet is a climate-resilient, drought-tolerant crop capable of growing in marginal
environments of arid and semi-arid regions globally. Pearl millet is a staple food for more
than 90 million people living in poverty and can address the triple burden of malnutrition
substantially. It remained a neglected crop until the turn of the 21st century, and much
emphasis has been placed since then on the development of various genetic and genomic
resources for whole-genome scan studies, such as the genome-wide association studies
(GWAS) and genomic selection (GS). This was facilitated by the advent of sequencingbased
genotyping, such as genotyping-by-sequencing (GBS), RAD-sequencing, and
whole-genome re-sequencing (WGRS) in pearl millet. To carry out GWAS and GS, a world
association mapping panel called the Pearl Millet inbred Germplasm Association Panel
(PMiGAP) was developed at ICRISAT in partnership with Aberystwyth University. This
panel consisted of germplasm lines, landraces, and breeding lines from 27 countries and
was re-sequenced using the WGRS approach. It has a repository of circa 29 million
genome-wide SNPs. PMiGAP has been used to map traits related to drought tolerance,
grain Fe and Zn content, nitrogen use efficiency, components of endosperm starch, grain
yield, etc. Genomic selection in pearl millet was jump-started recently by WGRS, RAD,
and tGBS (tunable genotyping-by-sequencing) approaches for the PMiGAP and hybrid
parental lines. Using multi-environment phenotyping of various training populations, initial
attempts have been made to develop genomic selection models. This mini review
discusses advances and prospects in GWAS and GS for pearl millet.","2020-02","published",,"Frontiers in Genetics (TSI)","10","1389","Frontiers Media",,"1-10",,,,,,"doi:10.3389/fgene.2019.01389",,,,,"TRUE",,"1664-8021",,,,,,"","https://doi.org/10.3389/fgene.2019.01389","https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=10.3389%2Ffgene.2019.01389&btnG=","pub",,"","",,,,,,"",,,,,,,"",,,,,"",,,,,"","",,,,,"","",,,,,
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