relation: http://oar.icrisat.org/11345/
title: Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns
creator: Pandey, A K
creator: Sudini, H
creator: Upadhyaya, H D
creator: Varshney, R K
creator: Pandey, M K
subject: Groundnut
subject: Genetics and Genomics
subject: Food and Nutrition
subject: Germplasm
description: Peanut allergy is one of the serious health concern and affects more than 1% of the  world’s population mainly in Americas, Australia, and Europe. Peanut allergy is sometimes  life-threatening and adversely affect the life quality of allergic individuals and their families.  Consumption of hypoallergen peanuts is the best solution, however, not much effort has  been made in this direction for identifying or developing hypoallergen peanut varieties.  A highly diverse peanut germplasm panel was phenotyped using a recently developed  monoclonal antibody-based ELISA protocol to quantify five major allergens. Results  revealed a wide phenotypic variation for all the five allergens studied i.e., Ara h 1 (4–36,833  μg/g), Ara h 2 (41–77,041 μg/g), Ara h 3 (22–106,765 μg/g), Ara h 6 (829–103,892 μg/g),  and Ara h 8 (0.01–70.12 μg/g). The hypoallergen peanut genotypes with low levels of  allergen proteins for Ara h 1 (4 μg/g), Ara h 2 (41 μg/g), Ara h 3 (22 μg/g), Ara h 6 (829 μg/g), and Ara h 8 (0.01 μg/g) have paved the way for their use in breeding and  genomics studies. In addition, these hypoallergen peanut genotypes are available for use in cultivation and industry, thus opened up new vistas for fighting against peanut allergy problem across the world.
publisher: Frontiers Media
date: 2019-11
type: Article
type: PeerReviewed
format: application/pdf
language: en
identifier: http://oar.icrisat.org/11345/1/fgene-10-01177.pdf
identifier:   Pandey, A K and Sudini, H and Upadhyaya, H D and Varshney, R K and Pandey, M K  (2019) Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns.  Frontiers in Genetics (TSI), 10 (1177).  pp. 1-15.  ISSN 1664-8021     
relation: https://doi.org/10.3389/fgene.2019.01177
relation: doi:10.3389/fgene.2019.01177