eprintid: 10301
rev_number: 12
eprint_status: archive
userid: 1305
dir: disk0/00/01/03/01
datestamp: 2017-11-21 11:08:32
lastmod: 2017-11-21 11:08:32
status_changed: 2017-11-21 11:08:32
type: conference_item
metadata_visibility: show
creators_name: Puranik, S
creators_name: Philliam, A G
creators_name: Ojulong, H
creators_name: Yadav, R
icrisatcreators_name: Ojulong, H
affiliation: Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University (Gogerddan)
affiliation: ICRISAT (Nairobi)
affiliation: NCBA CLUSA International (Kampala)
country: UK
country: Kenya
country: Uganda
title: Harnessing Benefits of Finger Millet in Combating Micronutrient Malnutrition through Genetics and Genomic Approaches
ispublished: pub
subjects: S1.5.2
subjects: s2.13
subjects: s2.17
subjects: s26
divisions: CRPS5
full_text_status: public
pres_type: paper
keywords: Finger millet, Micronutrients, Health benefitting traits, Genotyping-by sequencing, Genome-wide association study
abstract: In developing countries, 80% deaths are attributed to continuous persistence micronutrient deficiency and associated
infections and chronic diseases. Traditional crops harbouring health benefitting characteristics and micronutritional
richness can deliver a low cost sustainable food-based solution for nutrition and health in such countries. Finger
millet, one such traditional crop grown in most marginal areas of Africa and Asia, is a rich source of health
benefitting micronutrients, phytochemicals, vitamins and several essential amino acids. The objective of this work
is to use advances in genetics and genomics approaches for better understanding the genetic control of these
health benefitting traits and to breed them effectively into other staple crops consumed on daily basis. A set of
190 genotypes incorporating a minicore collection of finger millet together with a number of elite breeding lines
has been assembled to capture and characterise entire genetic variation associated with such traits in the crop
germplasm. These genotypes have been extensively characterised for diversity in micronutrients (such as iron,
zinc, calcium, magnesium, sodium, and potassium), protein and anti-nutrients (phytate and oxalate). Large-scale
GBS performed on this association panel has generated 156,157 SNPs which are being used in genome-wide
association studies. Our work has identified a number of genomic regions in finger millet associated with both
the health benefitting traits as well as with other factors that affect their bioavailability. This work will significantly
contribute in developing means of assessing how such genetic variations are distributed in other staple crops.
date: 2016-11
date_type: published
pagerange: 300
event_title: 1st International Agrobiodiversity Congress
event_location: New Delhi, India
event_dates: November 06-09, 2016
event_type: conference
refereed: TRUE
citation:   Puranik, S and Philliam, A G and Ojulong, H and Yadav, R  (2016) Harnessing Benefits of Finger Millet in Combating Micronutrient Malnutrition through Genetics and Genomic Approaches.  In: 1st International Agrobiodiversity Congress, November 06-09, 2016, New Delhi, India.     
document_url: http://oar.icrisat.org/10301/1/pages%20300.pdf