TY - JOUR AV - public A1 - Xia, Y A1 - Li, R A1 - Bai, G A1 - Siddique, K H M A1 - Varshney, R K A1 - Baum, M A1 - Yan, G A1 - Guo, P TI - Genetic variations of HvP5CS1 and their association with drought tolerance related traits in barley (Hordeum vulgare L.) UR - http://dx.doi.org/10.1038/s41598-017-08393-0 JF - Scientific Reports SN - 2045-2322 PB - Springer Nature N1 - This work was funded by the Provincial Key International Cooperative Research Platform and the Major Scientific Research Project of Guangdong Higher Education (2015KGJHZ015), and the Science and Technology Plan of Guangdong of China (2016B020201001). N2 - Delta-1-pyrroline-5-carboxylate synthase gene1 (P5CS1) is the key gene involved in the biosynthesis of proline and is significantly induced by drought stress. The exploration of genetic variation in HvP5CS1 may facilitate a better understanding of the mechanism of drought adaptation in barley. In the current study, 41 polymorphisms including 16 single nucleotide polymorphisms (SNPs) and 25 insertions/deletions (indels) were detected in HvP5CS1 among 287 barley (Hordeum vulgare L.) accessions collected worldwide, with 13 distinct haplotypes identified in the barley collection. Five polymorphisms in HvP5CS1 were significantly (P?