eprintid: 10115
rev_number: 11
eprint_status: archive
userid: 1305
dir: disk0/00/01/01/15
datestamp: 2017-07-31 10:49:36
lastmod: 2017-09-07 06:28:25
status_changed: 2017-07-31 10:49:36
type: article
metadata_visibility: show
creators_name: Puranik, S
creators_name: Kam, J
creators_name: Sahu, P P
creators_name: Yadav, R
creators_name: Srivastava, R K
creators_name: Ojulong, H F
creators_name: Yadav, R
icrisatcreators_name: Srivastava, R K
icrisatcreators_name: Ojulong, H F
affiliation: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University (Aberystwyth)
affiliation: ICRISAT (Patancheru)
affiliation: ICRISAT (Nairobi)
country: UK
country: India
country: Kenya
title: Harnessing Finger Millet to Combat Calcium Deficiency in Humans: Challenges and Prospects
ispublished: pub
subjects: S1
subjects: S1.5.2
subjects: ag2
subjects: s2.17
divisions: CRPS3
full_text_status: public
keywords: Finger Millet, Osteoporosis, Bioavailability, Food processing, Plant breeding,Calcium Deficiency, Genetic Improvement, Biofortification, Human Diet, Genetics, Human Health, Millet, Calcium
note: The authors wish to express their thanks to IBERS, UK for
the support in writing this manuscript. IBERS receives strategic
funding from BBSRC. SP acknowledges Marie Skłodowska-
Curie Individual Fellowship from Horizon 2020 of European
Commission (Project 657331; CaMILLET). We would also like
to acknowledge the editor and reviewers whose constructive
comments and suggestions helped to improve the manuscript.
abstract: Humans require more than 20 mineral elements for healthy body function. Calcium (Ca), one of the essential macromineral, is required in relatively large quantities in the diet for maintaining a sound overall health. Young children, pregnant and nursing women in marginalized and poorest regions of the world, are at highest risk of Ca malnutrition. Elderly population is another group of people most commonly affected by Ca deficiency mainly in the form of osteoporosis and osteopenia. Improved dietary intake of Ca may be the most cost-effective way to meet such deficiencies. Finger millet [Eleusine coracana (L.) Gaertn.], a crop with inherently higher Ca content in its grain, is an excellent candidate for understanding genetic mechanisms associated with Ca accumulation in grain crops. Such knowledge will also contribute toward increasing Ca contents in other staple crops consumed on daily basis using plant-breeding (also known as biofortification) methods. However, developing Ca-biofortified finger millet to reach nutritional acceptability faces various challenges. These include identifying and translating the high grain Ca content to an adequately bioavailable form so as to have a positive impact on Ca malnutrition. In this review, we assess some recent advancements and challenges for enrichment of its Ca value and present possible inter-disciplinary prospects for advancing the actual impact of Ca-biofortified finger millet.
date: 2017-07
date_type: published
publication: Frontiers in Plant Science
volume: 8
number: 1311
publisher: Frontiers Media
pagerange: 1-16
id_number: 10.3389/fpls.2017.01311
refereed: TRUE
issn: 1664-462X
official_url: http://dx.doi.org/10.3389/fpls.2017.01311
related_url_url: https://scholar.google.co.in/scholar?hl=en&q=Harnessing+Finger+Millet+to+Combat+Calcium+Deficiency+in+Humans%3A+Challenges+and+Prospects&btnG=
related_url_type: pub
citation:   Puranik, S and Kam, J and Sahu, P P and Yadav, R and Srivastava, R K and Ojulong, H F and Yadav, R  (2017) Harnessing Finger Millet to Combat Calcium Deficiency in Humans: Challenges and Prospects.  Frontiers in Plant Science, 8 (1311).  pp. 1-16.  ISSN 1664-462X     
document_url: http://oar.icrisat.org/10115/1/fpls-08-01311.pdf