Borgohain, T and Suma, R and Muttappagol, M and Saikia, B and Keithellakpam, A and Laskar, A and Hiremath, S S and Basu, U and Velmurugan, N and Palakolanu, S R and Chikkaputtaiah, C (2026) Precision breeding in a changing climate: unlocking resilience through omics and gene editing. Functional & Integrative Genomics. pp. 1-22. ISSN 1438-793X
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Abstract
Climate change, rising global food demand, and shrinking resources require transformative innovations in crop breeding. This review outlines recent advances in new breeding technologies (NBTs), including molecular markers, genome-wide association studies (GWAS), genomic selection (GS), next-generation sequencing (NGS), and gene editing (GE) tools such as the clustered regularly interspaced short palindromic repeat (CRISPR/Cas), base editing, and prime editing. These methods enable the accurate improvement of traits, thereby accelerating the development of crops resistant to both abiotic and biotic stresses. The integration of multi-omics platforms, including genomics, transcriptomics, proteomics, metabolomics, and phenomics, provides a comprehensive framework for deciphering and manipulating complex trait architectures. Artificial intelligence (AI) and machine learning (ML) enhance precision breeding by providing data-driven insights and enabling the forecasting of traits. Emphasis is also placed on combining gene editing with other strategies, such as speed breeding, to accelerate the development of traits. This review underscores the importance of an integrated systems biology approach that combines multi-omics, gene editing, AI, and speed breeding to accelerate the development of climate-resilient, high-yielding, and nutritionally enhanced crops. The integration of these innovative technologies holds great promise for addressing global food security, environmental sustainability, and agricultural resilience in the face of climate change. A strategic framework for the future of plant breeding is outlined, emphasizing the importance of interdisciplinary collaboration in building a sustainable agricultural future.
| Item Type: | Article |
|---|---|
| Divisions: | Global Research Program - Accelerated Crop Improvement |
| CRP: | UNSPECIFIED |
| Uncontrolled Keywords: | Climate-resilient crops, Gene editing, CRISPR/Cas, Omics integration, Speed breeding, Precision breeding |
| Subjects: | Others > Climate Smart Agriculture (CSA) Mandate crops > Groundnut Others > Genetics and Genomics |
| Depositing User: | Mr Nagaraju T |
| Date Deposited: | 20 Apr 2026 05:05 |
| Last Modified: | 20 Apr 2026 05:05 |
| URI: | http://oar.icrisat.org/id/eprint/13603 |
| Official URL: | https://link.springer.com/article/10.1007/s10142-0... |
| Projects: | Genome Editing for Crop Improvement |
| Funders: | Council of Scientific and Industrial Research (CSIR), Government of India, Department of Biotechnology (DBT), Government of India, Department of Science and Technology (DST), Government of India |
| Acknowledgement: | The authors are grateful to the Director, CSIR-North East Institute of Science and Technology (CSIR-NEIST), Jorhat, Assam, India, for providing encouragement and institutional support during the preparation of this review. All figures were created using BioRender.com. Manuscript No. NEIST/PUB/2025/130 Dated 31/07/2025. |
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