Nested Association Mapping (NAM) Populations: Present Status and Future Prospects in the Genomics Era

Gireesh, C and Sundarama, R M and Anantha, S M and Pandey, M K and Madhav, M S and Rathod, S and Yathish, K R and Senguttuvel, P and Kalyani, B M and Ranjith, E and Subbarao, L V and Mondal, T K and Swamy, M and Rakshit, S (2021) Nested Association Mapping (NAM) Populations: Present Status and Future Prospects in the Genomics Era. Critical Reviews in Plant Sciences, 40. pp. 49-67. ISSN 0735-2689

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Abstract

Development of mapping population is a prerequisite for genetic dissection of genomic regions underlying complex traits. Nested Association Mapping (NAM) is an integrated multi-parent population approach that combines the advantages of linkage mapping and association mapping for high resolution and high-power mapping of complex traits. The NAM population is constituent of independent RIL populations derived from crossing several diverse donor parents with a common founder parent. The first NAM population was developed in maize and later on in several crops like barley, sorghum, wheat, rice, soybean, etc. This review provides an overview of NAM population development, its features, advantages over the other mapping populations, availability of high density genotyping platforms, key considerations for their development, applications and future prospects. We propose that the recent high-throughput analytical tools including high-end genotyping will accelerate utilization of NAM population for prediction of genomic estimated breeding value and genomic assisted selection in crop improvement program.

Item Type: Article
Divisions: Center of Excellence in Genomics and Systems Biology
CRP: UNSPECIFIED
Uncontrolled Keywords: Combined linkage analysis and linkage disequilibrium, genomic prediction, GWAS, quantitative traits, multi-parent mapping population
Subjects: Others > Genetics and Genomics
Depositing User: Mr Nagaraju T
Date Deposited: 09 Jun 2025 08:47
Last Modified: 09 Jun 2025 08:47
URI: http://oar.icrisat.org/id/eprint/13134
Official URL: https://www.tandfonline.com/doi/abs/10.1080/073526...
Projects: UNSPECIFIED
Funders: UNSPECIFIED
Acknowledgement: The authors express sincere gratitude and immensely thank the reviewers of the journal for critical suggestions for improving the manuscript.
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