Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis

Anitha, S and Botha, R and Kane-Potaka, J and Givens, I D and Rajendran, A and Tsusaka, T W and Bhandari, R K (2021) Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis. Frontiers in Nutrition (TSI), 8 (700778). ISSN 2296-861X

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Many health benefits of millets (defined broadly to also include sorghum) have been advocated, including their roles in managing and preventing diabetes; however, the effects of millets on hyperlipidemia (high lipid levels) have been underrecognized. A systematic review and meta-analysis were conducted to collate available evidence of the impacts of millets consumption on lipid profile, namely total cholesterol (TC), triacylglycerol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and very-low–density lipoprotein cholesterol (VLDL-C). The results from 19 studies showed that the consumption of millets for periods as short as 21 days to 4 months reduced levels of TC, triacylglycerol, LDL-C, and VLDL-C (p<0.01) by 8.0, 9.5, 10 and 9.0%, respectively. Four studies demonstrated that millets consumption brought TC and triacylglycerol levels to the normal levels (<200 and <150 mg/dl, respectively). Furthermore, upon consumption of millet-based meals, there was a 6.0%increase in the HDL-C 4.0 and 5.0% reduction in systolic and diastolic blood pressure, and 7.0% reduction in body mass index (BMI). This evidence, leads us to conclude that consumption of millets reduces hyperlipidemia and hence hypertension, and raises the levels of HDL-C (good cholesterol), which can be beneficial for managing the associated risk of developing hypertension and atherosclerotic cardiovascular diseases in future.

Item Type: Article
Divisions: Strategic Marketing and Communication
Uncontrolled Keywords: Millets, hyperlipidemia, cholesterol, triacylglycerol, lipid profile
Subjects: Others > Smart Foods
Mandate crops > Millets
Depositing User: Mr Ramesh MNR
Date Deposited: 15 Jun 2022 03:36
Last Modified: 22 Jun 2022 09:32
Official URL:
Acknowledgement: The authors would like to acknowledge Dr. Jali MV who sent in missing data to support this meta-analysis, and Dr. Ram B Singh who clarified having used finger millet in his study. The authors acknowledge Ms. Rajani Kumar, ICRISAT, for editing the manuscript. The authors also thank Mr. Ramesh Kotnana for sourcing scientific articles.
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